A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction (vol 62, pg 5298, 2019)

Roy Saktimayee M.; Minasov George; Arancio Ottavio; Chico Laura W.; Van Eldik Linda J.; Anderson Wayne F.; Pelletier Jeffrey C.; Watterson D. Martin

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A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction (vol 62, pg 5298, 2019)

机译：一种选择性和脑渗透P38αMapk抑制剂候选神经系统和神经精神疾病，可衰减神经炎炎症和认知功能障碍（Vol 62，PG 5298,2019）

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来源
《Journal of Medicinal Chemistry》 |2020年第15期|共1页
作者
Roy Saktimayee M.; Minasov George; Arancio Ottavio; Chico Laura W.; Van Eldik Linda J.; Anderson Wayne F.; Pelletier Jeffrey C.; Watterson D. Martin;
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正文语种 eng
中图分类药学;
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1. A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction (vol 62, pg 5298, 2019) [J] . Roy Saktimayee M., Minasov George, Arancio Ottavio, Journal of Medicinal Chemistry . 2020,第15期

机译：一种选择性和脑渗透P38αMapk抑制剂候选神经系统和神经精神疾病，可衰减神经炎炎症和认知功能障碍（Vol 62，PG 5298,2019）
2. Targeting neuroinflammation with brain penetrant P2X7 antagonists as novel therapeutics for neuropsychiatric disorders [J] . Anindya Bhattacharya, Marc Ceusters Neuropsychopharmacology . 2020,第1期

机译：用脑渗透剂P2X7拮抗剂靶向神经炎症作为神经精神疾病的新疗效
3. Discovery and optimization of Lu AF58801, a novel, selective and brain penetrant positive allosteric modulator of alpha-7 nicotinic acetylcholine receptors: Attenuation of subchronic phencyclidine (PCP)-induced cognitive deficits in rats following oral administration [J] . EskildsenJ., RedrobeJ.P., SamsA.G., Bioorganic and Medicinal Chemistry Letters . 2014,第1期

机译：发现和优化Lu AF58801，一种新型的，选择性的，脑渗透性的α-7烟碱乙酰胆碱受体正变构调节剂：口服后大鼠亚慢性苯环利定（PCP）引起的认知功能障碍的减轻
4. A Selective andBrain Penetrant p38αMAPK InhibitorCandidate for Neurologic and Neuropsychiatric Disorders That AttenuatesNeuroinflammation and Cognitive Dysfunction [O] . SaktimayeeM. Roy, George Minasov, Ottavio Arancio, -1

机译：选择性和脑渗透性p38αMAPK抑制剂减轻神经系统疾病和神经精神疾病的候选人神经炎症和认知功能障碍
5. Correction to “A Selective and Brain Penetrant p38αMAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction” [O] . Saktimayee M. Roy, George Minasov, Ottavio Arancio, 2020

机译：校正“一种选择性和脑渗透P38αmapk抑制剂的神经系统和神经精神疾病的候选者，其衰减神经炎性和认知功能障碍”

A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction (vol 62, pg 5298, 2019)

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