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Long-Term Efficacy of Initial Microvascular Decompression Versus Subsequent Microvascular Decompression for Idiopathic Hemifacial Spasm

机译:初始微血管减压的长期疗效与特发性半侵蚀痉挛的后续微血管减压

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摘要

Objective Hemifacial spasm (HFS) is a disorder characterized by intermittent, involuntary facial muscle contractions. Microvascular decompression (MVD) is the gold treatment for HFS. The aim of this research was to discuss whether patients undergoing MVD as their initial surgical intervention experience greater spasm control than patients experiencing an MVD performed as a subsequent surgical intervention. Methods The study included 976 patients with HFS, 452 of whom (group A) underwent MVD as their initial surgical intervention and 524 of whom (group B) underwent subsequent MVD. Relevant clinical data including outcome of MVD, operative findings, complications, and so on were collected immediately after MVD operation and at follow-up. Results The follow-up period was 7–9 years (mean, 7.96 ± 0.87 years). The mean age at intervention was 53.14 years and 55.43 years in the 2 groups, respectively. The long-term postoperative relief rate of patients in the 2 groups was 98.23% and 87.21%, respectively. There was a significant difference in long-term postoperative relief rate of patients between the 2 groups ( P Conclusions Patients undergoing MVD for HFS as the primary treatment experience better long-term efficacy than patients first treated with botulinum neurotoxin type?A.
机译:客观的半衰期痉挛(HFS)是一种疾病,其特征是间歇性的非自愿面部肌肉收缩。微血管减压(MVD)是HFS的金色处理。本研究的目的是讨论是否患者作为其初始手术干预的患者是否经历了比经过随后进行的手术干预所进行的MVD的患者更大的痉挛控制。方法该研究包括976例HFS,其中452名患者(A组)接受MVD作为其初始手术干预,其中524人(B组)接受了后续的MVD。在MVD操作和随访后立即收集包括MVD,手术结果,并发症等结果的相关临床数据。结果后续期为7-9岁(平均值,7.96±0.87岁)。干预的平均年龄分别为53.14岁,分别为2组55.43岁。 2组患者的长期术后缓解率分别为98.23%和87.21%。两组患者的长期术后缓解率显着差异(P结论是HFS的MVD患者,因为初级治疗经历了比肉毒杆菌神经毒素类型首次处理的患者更好的长期疗效?a。

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  • 来源
    《World neurosurgery》 |2018年第2018期|共5页
  • 作者单位

    Department of Neurosurgery XinHua Hospital Affiliated to Shanghai Jiao Tong University School of;

    Department of Neurosurgery Liaocheng People's Hospital;

    Department of Neurosurgery XinHua Hospital Affiliated to Shanghai Jiao Tong University School of;

    Department of Neurosurgery XinHua Hospital Affiliated to Shanghai Jiao Tong University School of;

    Department of Neurosurgery XinHua Hospital Affiliated to Shanghai Jiao Tong University School of;

    Department of Neurosurgery XinHua Hospital Affiliated to Shanghai Jiao Tong University School of;

    Department of Neurosurgery XinHua Hospital Affiliated to Shanghai Jiao Tong University School of;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 外科学各论;
  • 关键词

    Botulinum neurotoxin type A; Hemifacial spasm; Long-term efficacy; Microvascular decompression;

    机译:肉毒杆菌神经毒素型;半侵蚀;长期疗效;微血管减压;

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