The effects of gliclazide, methylcobalamin, and gliclazide plus methylcobalamin combination therapy on diabetic peripheral neuropathy in rats

Yao Hongping; Feng Juanyi; Zheng Qiaowei; Wei Youxia; Wang Shixiang; Feng Weiyi

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The effects of gliclazide, methylcobalamin, and gliclazide plus methylcobalamin combination therapy on diabetic peripheral neuropathy in rats

机译：Gliclazide，甲基丙胺素和Gliclazide加上甲基钴胺联合治疗对大鼠糖尿病周围神经病变的影响

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Aims: This study investigated the efficacies of gliclazide (GLZ), methylcobalamin (MCA), and GLZ + MCA combination therapy on DPN by evaluating the treatment-related changes in peripheral nerve function, the polyol pathway, and oxidative stress in the sciatic nerve of streptozotocin-induced diabetic rats.

机译：目的：本研究通过评估外周神经功能，多元醇途径和坐骨神经中的氧化胁迫来研究Gliclazide（GLZ），甲基丙氨酸（MCA），甲基钴胺（MCA）和GLZ + MCA组合治疗的疗效。链脲佐菌素诱导的糖尿病大鼠。

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来源
《Life sciences》 |2016年第null期|共9页
作者
Yao Hongping; Feng Juanyi; Zheng Qiaowei; Wei Youxia; Wang Shixiang; Feng Weiyi;
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作者单位

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Xian 710061 Peoples R China;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 2 Xian 710004 Peoples R China;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Xian 710061 Peoples R China;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Xian 710061 Peoples R China;

Northwest Univ Coll Life Sci Xian 710069 Peoples R China;

Xi An Jiao Tong Univ Coll Med Affiliated Hosp 1 Xian 710061 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
关键词
Diabetic peripheral neuropathy; Gliclazide; Methylcobalamin;

机译：糖尿病外周神经病变;Gliclazide;甲基丙二酸;

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1. The effects of gliclazide, methylcobalamin, and gliclazide plus methylcobalamin combination therapy on diabetic peripheral neuropathy in rats [J] . Yao Hongping, Feng Juanyi, Zheng Qiaowei, Life sciences . 2016,第Null期

机译：Gliclazide，甲基丙胺素和Gliclazide加上甲基钴胺联合治疗对大鼠糖尿病周围神经病变的影响
2. Prostaglandin E1 plus methylcobalamin combination therapy versus prostaglandin E1 monotherapy for patients with diabetic peripheral neuropathy: A meta-analysis of randomized controlled trials [J] . De-Qi Jiang, Shi-Hua Zhao, Ming-Xing Li, Medicine. . 2018,第44期

机译：前列腺素E1 +甲基钴胺素联合治疗与前列腺素E1单药治疗糖尿病周围神经病变的患者：一项随机对照试验的荟萃分析
3. Effects of prostaglandin E1 plus methylcobalamin alone and in combination with lipoic acid on nerve conduction velocity in patients with diabetic peripheral neuropathy: A meta-analysis [J] . Jiang De-Qi, Li Ming-Xing, Wang Yan, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2015,第Null期

机译：前列腺素E1加甲基钴胺素单独或与硫辛酸联用对糖尿病周围神经病患者神经传导速度的影响：荟萃分析
4. Evaluation of Rate of Muscular Force Development in Type 2 Diabetic Individuals with and without Diabetic Peripheral Neuropathy [C] . M. A. Favretto, S. Cossul, F. R. Andreis Brazilian Congress on Biomedical Engineering . 2019

机译：2型糖尿病患者肌肉力发育率的评价，患有糖尿病外周神经病变的2型糖尿病个体
5. Coping with diabetic peripheral neuropathy: A pilot study examining the impact of coping styles, acceptance, and optimism on the outcome of thermal biofeedback therapy. [D] . Scherdell, Traci. 2010

机译：应对糖尿病周围神经病变：一项初步研究，探讨应对方式，接受度和乐观度对热生物反馈疗法的影响。
6. Prostaglandin E1 plus methylcobalamin combination therapy versus prostaglandin E1 monotherapy for patients with diabetic peripheral neuropathy [O] . De-Qi Jiang, Shi-Hua Zhao, Ming-Xing Li, -1

机译：前列腺素E1 +甲基钴胺素联合治疗与前列腺素E1单药治疗糖尿病周围神经病
7. Evaluation of efficacy and safety of epalrestat and epalrestat in combination with methylcobalamin in patients with diabetic neuropathy in a randomized, comparative trial [O] . Anil Bhoraskar, Datta Zemse, Aziz A. Mhate, 2013

机译：在一项随机对照试验中评估依帕司他和依帕司他联合甲基钴胺素在糖尿病神经病变患者中的疗效和安全性

The effects of gliclazide, methylcobalamin, and gliclazide plus methylcobalamin combination therapy on diabetic peripheral neuropathy in rats

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