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Global control of cell growth in fission yeast and its coordination with the cell cycle

机译:裂变酵母中细胞生长的整体控制及其与细胞周期的协调

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摘要

Cell growth is a fundamental process for every cell but its pleiotropic complexity makes it difficult to comprehend. Global aspects of cellular growth, like the overall determinants of growth rate are not well understood. Here we examine the cell growth pattern of the fission yeast Schizosaccharomyces pombe during the mitotic and meiotic cell cycles. We also explore recent findings illuminating aspects of cell size homeostasis and cell growth regulation, and propose that there are global controls over growth acting at the level of the cell.
机译:细胞生长是每个细胞的基本过程,但其多效性的复杂性使其难以理解。细胞生长的全局方面,如生长速率的总体决定因素,尚未得到很好的理解。在这里,我们检查裂殖酵母裂殖酵母在有丝分裂和减数分裂细胞周期中的细胞生长模式。我们还探索了最近的发现,这些发现阐明了细胞大小稳态和细胞生长调节的各个方面,并提出了对生长在细胞水平上的生长具有全局控制。

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