Mucus' Effects on Inflammation May Be Used to Treat Gut Diseases

摘要

The researchers analyzed mucus from mice, pigs, and a human intestinal cell line. By giving mucus from healthy mice to mice lacking intestinal mucus and to mice with colitis, they found that the presence of mucus stimulated production of anti-inflammatory cytokines and prevented bacteria from inducing an immune response. These effects seemed to involve regulation of pathways involving molecules such as nuclear factor-i