Visible light photoredox-catalyzed alkylation/ring expansion sequences of 1-(1-arylvinyl)cyclobutanol derivatives

摘要

A visible light-mediated photocatalytic bis(alkoxycarbonypmethylationtring expansion of alkenyl cyclobutanols is described. This approach provides a mild and operationally simple access to the synthesis of bis(alkoxycarbonyl)methyl-substituted cyclic ketones from the coupling reaction of 1-(1-arylvinyl)cyclobutanols with aryl bromomalonates. (C) 2016 Elsevier Ltd. All rights reserved.