First stereoselective total synthesis of pectinolide C and total synthesis of pectinolide A

摘要

The first stereoselective synthesis of pectinolide C and synthesis of pectinolide A, from easily accessible 1 -hexyne and D-mannitol are reported in a convergent manner. The salient features include acetylenic addition to the chiral aldehyde and Still-Gennari olefination.