Rhodium-catalyzed alkylation of terephthaldialdimine with terminal alkenes via C-H bond activation

摘要

Terephthaldialdimine la reacted with alkenes to give 2,6-dialkylated products selectively in moderate to high isolated yields.In the case of terephthaldialdimine 1b having a substituent at site 2 in the phenyl ring,the alkylation takes place selectively at site 6 in the phenyl ring.In this alkylation,a meta-substituent affected the reactivity significantly because of the steric hindrance.