Synthesis and Antibacterial Studies of 1-[3-(Trifluoromethoxy)-phenylmethanone]piperidine-4-carboxylic Acid Derivatives

摘要

Synthesis of novel piperidine-4-carboxamide derivatives as antibacterial agents has elevated impact on medicinal field. In the present work, ten new compounds were synthesized and screened toward their antibacterial studies. The structures of these compounds were characterized and analyzed by spectral studies such as IR, mass and ~1H NMR and compounds 6a and 6c-6h, were observed to possess potent antimicrobial activity.