首页> 外文学位 >I. A1,3- strain enabled retention of chirality during Bis-cyclization of β-ketoamides: Asymmetric synthesis and bioactivity of salinosporamide a and derivatives II. Optimization of an Organic syntheses procedure: asymmetric nucleophile-catalyzed aldol-lactonization with aldehyde acids

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I. A1,3- strain enabled retention of chirality during Bis-cyclization of β-ketoamides: Asymmetric synthesis and bioactivity of salinosporamide a and derivatives II. Optimization of an Organic syntheses procedure: asymmetric nucleophile-catalyzed aldol-lactonization with aldehyde acids

机译：I. A1,3-菌株能够在β-酮基酰胺的双环化过程中保留手性：salinosporamide a和衍生物II的不对称合成和生物活性。有机合成程序的优化：醛酸不对称亲核催化醛醇内酯化

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作者
Nguyen, Henry;
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作者单位

Texas A&M University;

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授予单位 Texas A&M University;
学科
学位 Ph.D.
年度 2010
页码 255 p.
总页数 255
原文格式 PDF
正文语种 eng
中图分类
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入库时间 2022-08-17 11:55:58

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1. A~(1,3)-strain enabled retention of chirality during bis-cyclization of β-ketoamides: total synthesis of (-)-salinosporamide A and (-)-homosalinosporamide A [J] . Henry Nguyen, rnGil Ma, rnDaniel Romo Chemical Communications . 2010,第26期

机译：A〜（1,3）菌株可在β-酮基酰胺双环化过程中保持手性：（-）-水杨孢酰胺A和（-）-高芥子酰胺A的全合成
2. Chiral salen-Aluminum Complexes as Catalysts for Enantioselective Aldol Reactions of Aldehydes and 5-Alkoxyoxazoles: An Efficient Approach to the Asymmetric synthesis of syn and anti #beta#-Hydroxy-#alpha#-amino Acid Derivatives [J] . David A.Evans, Jacob M.Janey, Nabi Magomedov, Chembiochem: A European journal of chemical biology . 2001,第10期

机译：手性盐 - 铝配合物作为醛和5-烷氧基氧氮的对映选择性醛醇反应的催化剂：一种有效的方法，用于同次和抗＃-α-α＃--amino酸衍生物的不对称合成
3. Part I. Asymmetric synthesis of bicyclic analogues of risedronate as molecular probes of the mechanism of action of bisphosphonate antiosteoporotic drugs and potentially more efficacious antiosteoporotic agents. Part II. Facile preparation and functionalization of chiral stabilized ylides from common chiral auxiliaries using the Bestmann ylide and their use in Wittig reactions. Part III. Asymmetric organocatalysis: 1. An investigation of alpha-hydroxylation of aldehydes; 2. Synthesis of a novel camphor-based alpha-aminotetrazole organocatalyst. [D] . Song, Xinyi. 2007

机译：第一部分：利塞膦酸盐双环类似物的不对称合成，作为双膦酸盐类抗骨质疏松药和潜在更有效的抗骨质疏松药作用机理的分子探针。第二部分使用Bestmann内酯从常见手性助剂轻松制备和官能化手性稳定化的叶基及其在Wittig反应中的用途。第三部分不对称有机催化：1.醛的α-羟基化研究； 2.合成新的基于樟脑的α-氨基四唑有机催化剂。
4. A13-strain enabled retention of chirality during bis-cyclization of β-ketoamides: total synthesis of (−)-salinosporamide A and (−)-homosalinosporamide A [O] . Henry Nguyen, Gil Ma, Daniel Romo -1

机译：期间β酮酰胺的双 - 环化a13应变启用手性的保留：总合成（ - ） - salinosporamide a和（ - ） - homosalinosporamide甲
5. I. A1,3-Strain Enabled Retention of Chirality During Bis-Cyclization of ?-Ketoamides: Asymmetric Synthesis and Bioactivity of Salinosporamide A and Derivatives II. Optimization of an Organic Syntheses: Asymmetric Nucleophile-Catalyzed Aldol- Lactonization of Aldehyde Acids [O] . Nguyen Henry 2013

机译：I.α-酮酰胺双环化过程中A1，3-菌株的手性保留：盐孢子酰胺A及其衍生物的不对称合成及其生物活性II。有机合成的优化：醛酸的不对称亲核催化醛醇缩醛化

I. A1,3- strain enabled retention of chirality during Bis-cyclization of β-ketoamides: Asymmetric synthesis and bioactivity of salinosporamide a and derivatives II. Optimization of an Organic syntheses procedure: asymmetric nucleophile-catalyzed aldol-lactonization with aldehyde acids

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