Adverse Events Associated With Intravenous Iron Preparations: A Comparison of Reported Rates

摘要

H&O What are the most common intravenous iron preparations used in the United States?GB Several intravenous (IV) iron preparations are widely used in the United States. Iron dextran is available in 2 variants: high-molecular weight (Dexferrum, American Regent) and low-molecular weight (INFeD, Watson). Sodium ferric gluconate is available in its original version (Ferrlecit, Sanofi-Aventis) and a newer generic formulation (Nulecit, Watson). Other preparations are iron sucrose (Venofer, American Regent/Fresenius Medical Care) and the newest agent, ferumoxytol (Feraheme, AMAG), which was approved in 2009. There are some significant differences among these iron preparations, which I will discuss.