細胞伸展制御のためのPETフィルム表面へのナノ周期構造の形成

摘要

Periodic nanostructures were created on a polyethylene terephthalate (PET) film surface with a femtosecond laser to control cell spreading. Controlling cell spreading on PET surface would contribute to the creation of advanced biomaterials. The PET film was bonded with the Si wafer, as a pre-treatment. A silicon wafer was irradiated with the femtosecond laser through the PET film. After the irradiation, periodic nanostructures were produced on the PET film surface. The period and groove depth of the periodic nanostructure on the PET were about 600 nm and 100 nm, respectively. In a cell test on the PET film, cell spreading was observed with a fluorescence microscope. 71% of cells were spread along the grooves on the PET.