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首页> 外文期刊>Clinical and experimental ophthalmology >Long-term evaluation of trabeculectomy in primary open angle glaucoma and chronic primary angle closure glaucoma in an Asian population.
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Long-term evaluation of trabeculectomy in primary open angle glaucoma and chronic primary angle closure glaucoma in an Asian population.

机译:对亚洲人群原发性开角型青光眼和慢性原发性闭角型青光眼的小梁切除术进行长期评估。

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摘要

Purpose: A retrospective cohort study was undertaken to evaluate and compare the long-term results of trabeculectomy in primary open angle glaucoma (POAG) and chronic primary angle closure glaucoma (CPACG) in an Asian population. Methods: Yearly diurnal measurements of intraocular pressure (IOP), best-corrected visual acuity, optic disc and visual field records of patients having primary adult glaucomas who had undergone trabeculectomy, without anti-mitotic agents, with a minimum of 5 years follow up were evaluated. Only one eye of each patient was studied. The success rates for IOP control in POAG and CPACG were statistically analysed. Results: Sixty-four eyes of 64 patients were studied. The overall probability of success of trabeculectomy in controlling IOP to
机译:目的:进行一项回顾性队列研究,以评估和比较亚洲人群小梁切除术治疗原发性开角型青光眼(POAG)和慢性原发性闭角型青光眼(CPACG)的长期效果。方法:对患有原发性青光眼并经小梁切除术且无抗有丝分裂剂的患者进行眼内压(IOP),最佳矫正视力,视盘和视野记录的每日昼夜测量,至少随访5年评估。每个病人只研究一只眼睛。对POAG和CPACG中IOP控制的成功率进行了统计分析。结果:对64例患者的64只眼进行了研究。在有或没有额外的局部抗青光眼药物治疗的情况下,小梁切除术成功控制眼压至≤21mmHg的总概率分别为5岁和10岁,分别为0.94和0.88。在POAG和CPACG眼之间,眼压控制的合格率和绝对成功率在统计学上无显着差异(对数秩检验P分别为0.6、0.88)。与26只POAG眼中的四只眼相比,十二只38只CPACG眼的视力下降了两行(P = 0.17)。白内障的进展或发展是视力下降的最常见原因。结论:在POAG和CPACG中,不使用抗代谢物的小梁切除术在降低IOP和保持视野10年中似乎是有效的。白内障的发展/进展,特别是小梁切除术后慢性闭角型青光眼的白内障必须被视为重要问题。

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