CORR insights?: Does vitamin D improve osteoarthritis of the knee: A randomized controlled pilot trial

摘要

Where Are We Now?: The increased prevalence of osteoarthritis in Western countries is due, in part, to an aging and gradually more obese population. Obesity is a major risk factor for knee and to a lesser extent, hip osteoarthritis. The rates of disease are rising faster than can be explained by aging and obesity. This increase may be ascribed to sports-related injury or an unwillingness of patients to accept even modest joint pain that in the past probably did not trigger medical care [7]. Rates of knee replacement are rising rapidly. Effective nonsurgical treatments are desperately needed, but no treatments for osteoarthritis have been consistently shown to slow the course of disease, and there are few symptom modifying treatments considered effective - most, like exercise treatment, come with compliance issues.