首页> 外文期刊>Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology >Post-thrombolysis haemostasis changes after rt-PA treatment in acute cerebral infarct. Correlations with cardioembolic aetiology and outcome
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Post-thrombolysis haemostasis changes after rt-PA treatment in acute cerebral infarct. Correlations with cardioembolic aetiology and outcome

机译:rt-PA治疗急性脑梗死后溶栓后止血改变。与心脏栓塞病因和预后的关系

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摘要

Background: Little is known, in man, in the post-thrombolytic molecular dynamics of haemostasis, particularly the effect of rt-PA on antifibrinolytic components such as alpha2 anti-plasmin and Factor XIII. Aims and hypothesis: The purpose of this study was to systematically determine changes in coagulation and fibrinolytic parameters after thrombolysis with rt-PA during 24 h. We also aimed to correlate these parameters with different acute ischemic stroke subtypes and global outcome.
机译:背景:在人类中,止血后的溶栓后分子动力学,尤其是rt-PA对抗纤溶蛋白成分(如α2抗纤溶酶和因子XIII)的作用,鲜为人知。目的和假设:本研究的目的是系统地测定rt-PA溶栓24小时后凝血和纤溶参数的变化。我们还旨在将这些参数与不同的急性缺血性卒中亚型和整体预后相关联。

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