H-1 NMR-based metabonomics revealed protective effect of Naodesheng bioactive extract on ischemic stroke rats

摘要

Ethnopharmacological relevance: Stroke is a leading cause of death and disability in the world. However, current therapies are limited. Naodesheng, a widely used traditional Chinese medicine prescription, has shown a good clinical curative effect on ischemic stroke. Also, Naodesheng has been suggested to have neuroprotective effect on focal cerebral ischemia rats, but the underlying molecular mechanism remains unclear.