Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats

Ma Jiang; Zheng Li; He Yi-Sheng; Li Hui-Jun

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Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats

机译：何首乌提取物的肝毒性评价及苷和蒽醌的毒动力学研究。

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Ethnopharmacological relevance: Polygoni Multiflori Radix (PMR) has been traditionally used as a tonic and an anti-aging remedy for centuries; however, hepatic lesions linked to PMR have been frequently reported.

机译：人种药理学相关性：百日草（Polygoni Multiflori Radix（PMR））传统上已被用作滋补品和抗衰老药物，已有数百年历史。然而，与PMR相关的肝病变已被频繁报道。

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《Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs》 |2015年第null期|共8页
作者
Ma Jiang; Zheng Li; He Yi-Sheng; Li Hui-Jun;
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正文语种 eng
中图分类药理学;
关键词
Polygoni Multiflori Radix; Extensive consumption; Hepatocellular damage; Toxicokinetics; Emodin exposure;

机译：何首乌;大量食用;肝细胞损伤;毒代动力学;大黄素暴露;

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专利

1. Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats [J] . Ma Jiang, Zheng Li, He Yi-Sheng, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2015,第Null期

机译：何首乌提取物的肝毒性评价及苷和蒽醌的毒动力学研究。
2. Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism [J] . Lin Li, Hao Zhanxia, Zhang Shaobo, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2020,第期

机译：Polygoni Multiflori adrix和Polygoni multiflori桡脂水提取物保护对NAFLD及其机制的研究
3. The assessment of the chronic hepatotoxicity induced by Polygoni Multiflori Radix in rats: A pilot study by using untargeted metabolomics method [J] . Xia Xin-Hua, Yuan Yuan-Yuan, Liu Mei Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2017,第期

机译：大鼠聚四米多氟化糖诱导的慢性肝毒性评估：使用未标准的代谢组种方法的试验研究
4. Gradient Elution Separation Of Main Ingredients From Polygoni Multiflori Extract By HPLC [C] . Tao Wang International Conference on Energy, Environment and Sustainable Development . 2014

机译：HPLC从Polygoni multiflli提取物中梯度洗脱分离主要成分
5. The Studies of Ultrasound Enhancement on Ultrafiltration for Radix astragalus Extracts and Cleaning of Fouled Membane. [D] . Cai, Ming. 2011

机译：超声波增强黄芪提取物超滤效果及膜污染的研究。
6. Hepatotoxicity in Rats Induced by Aqueous Extract of Polygoni Multiflori Radix Root of Polygonum multiflorum Related to the Activity Inhibition of CYP1A2 or CYP2E1 [O] . Deng-Ke Li, Jing Chen, Zhen-Zhen Ge, 2017

机译：何首乌水提物何首乌根提取物诱导的大鼠肝毒性与CYP1A2或CYP2E1活性的抑制有关
7. Metabolomics profiling of Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata extracts using UPLC-Q/TOF-MS [O] . Zhaoyan Zhang, Liang Yang, Xiaoyan Huang, 2019

机译：使用UPLC-Q / TOF-MS的Polygoni Multiflori radix和Polygoni Multiflori adrix提取的代谢组织分析

Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats

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