Long-Terra Efficacy of Olmesartan Medoxomil in Chinese Hypertensive Patients as Assessed by Clinic, Ambulatory and Home Blood Pressure Measurements

摘要

Background and Objectives There is limited information on the long-term efficacy and safety of olmesartan me-doxomil in the management of hypertension in Chinese patients. We therefore conducted the present multicentre, single-arm, prospective, observational study to investigate the 24-week efficacy and safety of olmesartan medoxomil in patients with mild to moderate hypertension. Methods Eligible patients (diastolic blood pressure [BP] 90-109 mmHg and systolic BP <180 mmHg off antihy-pertensive medication) were started on olmesartan medoxomil 20 mg once daily, with the possible up-titration to 40 mg once daily during 24 weeks of follow-up, to control clinic BP to the target level (<140/90 and <130/80 mmHg in diabetes mellitus).