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Role of miR-107 and its signaling pathways in diseases

机译:miR-107及其信号传导途径在疾病中的作用

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摘要

MicroRNAs exert their biologic effects by targeting specific mRNAs for degradation or translational inhibition. MicroRNA-mediated regulation is complex, potentially affecting expression of the host gene, related enzymes within the same pathway or apparently distinct targets. miR-107 is found to be implicated in the pathogenesis of some diseases. This review was performed to sum up the role of miR-107 and its signaling pathways in renal diseases.
机译:MicroRNA通过靶向特定的mRNA进行降解或翻译抑制而发挥其生物学作用。 MicroRNA介导的调控是复杂的,可能影响宿主基因,同一途径内的相关酶或明显不同靶标的表达。发现miR-107与某些疾病的发病机制有关。进行此综述以总结miR-107及其信号传导途径在肾脏疾病中的作用。

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