首页> 外文期刊>Journal of Periodontology >Periodontal disease and recurrent cardiovascular events in survivors of myocardial infarction (MI): the Western New York Acute MI Study.
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Periodontal disease and recurrent cardiovascular events in survivors of myocardial infarction (MI): the Western New York Acute MI Study.

机译:心肌梗死幸存者的牙周疾病和复发性心血管事件:纽约西部急性心肌梗死研究。

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BACKGROUND: Periodontal disease and cardiovascular disease (CVD) have been the focus of much research, but little is known about their roles in the recurrent event risk in patients with CVD. This study investigates whether periodontal disease is related to recurrent CVD events and mortality in survivors of incident myocardial infarction (MI). METHODS: Participants (668 males and 216 females; mean age: 54 + or - 8.5 years) were recruited (1997 through 2004) from two western New York county hospitals and completed an interviewer-administered questionnaire regarding lifestyle habits, clinical measurements, and a comprehensive dental examination. The periodontal disease status was measured by the mean clinical attachment loss (AL). Follow-up surveys assessed hospitalizations or medical procedures; cardiovascular events were validated by medical records. A National Death Index (NDI) Plus search was conducted. The outcome was recurrent fatal and non-fatal cardiovascular events (International Classification of Diseases codes 390 to 450). RESULTS: After an average follow-up of 2.9 years, 154 events were reported. Among never-smokers, the adjusted hazard ratio (95% confidence interval) for the mean clinical AL (millimeters) was 1.43 (1.09 to 1.89). No associations were found in ever-smokers (clinical AL by smoking interaction: P <0.05). CONCLUSION: These findings indicate that periodontal disease may be an important factor in determining recurrent cardiovascular events in MI patients and not merely a marker for the effects of cigarette smoking.
机译:背景:牙周疾病和心血管疾病(CVD)一直是许多研究的重点,但对于它们在CVD患者复发事件风险中的作用知之甚少。这项研究调查了牙周疾病是否与复发性CVD事件以及事件性心肌梗死(MI)幸存者的死亡率有关。方法:从纽约西部两个县医院(1997年至2004年)招募参与者(男668例,女216例;平均年龄:54岁或8.5岁),并完成了由访调员管理的关于生活习惯,临床测量和健康状况的问卷。综合牙科检查。牙周疾病状态通过平均临床依恋丧失(AL)进行衡量。跟踪调查评估住院或医疗程序;心血管事件已通过医疗记录验证。进行了国家死亡指数(NDI)Plus搜索。结果是反复发生的致命和非致命性心血管事件(国际疾病分类代码390至450)。结果:平均随访2.9年后,报告了154起事件。在从未吸烟者中,平均临床AL(毫米)的调整后危险比(95%置信区间)为1.43(1.09至1.89)。在无烟者中未发现关联(通过吸烟相互作用的临床AL:P <0.05)。结论:这些发现表明,牙周疾病可能是决定MI患者反复发生心血管事件的重要因素,而不仅仅是吸烟效果的标志。

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