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Unintentional injuries in a twin study of preschool children: environmental, not genetic, risk factors.

机译:在一项对学龄前儿童的双胞胎研究中,意外伤害是环境危险因素,而不是遗传因素。

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OBJECTIVE: To analyze the relative contribution of latent genetic and environmental factors to differences in the injury liability of children, and to examine the association between measured socio-economic, family, and child-behavior variables and unintentional injury risk. METHODS: Unintentional injuries from birth to age 5, together with information regarding measured risk variables, were reported by mothers in a sample of 1027 same-sex twin pairs from a nationally representative 1994-1995 birth cohort. RESULTS: Child-specific environmental factors accounted for most of the variance (86.4%) in the likelihood of ever having an injury. When considering the risk of two or more injuries child-specific environmental factors explained 60.2% of the variance and family-wide environmental influence 39.8%. Measured socio-economic, family, and child-behavior factors predicted frequent injury. CONCLUSIONS: Results give little support to the concept of a heritable injury-prone trait in preschool children; environmental influences accounted for most of the injury variance in this sample. However, behavioral variables, especially the child's externalizing problem behaviors, are also important in explaining unintentional injuries.
机译:目的:分析潜在的遗传和环境因素对儿童伤害责任差异的相对贡献,并检验社会经济,家庭和儿童行为变量与无意伤害风险之间的关系。方法:母亲从全国有代表性的1994-1995年出生队列的1027对同性双胞胎样本中报告了从出生到5岁的意外伤害以及有关测得的风险变量的信息。结果:儿童特定环境因素占受伤可能性的大部分(86.4%)。考虑两个或两个以上伤害的风险时,儿童特定的环境因素可解释60.2%的差异,而整个家庭范围内的环境影响则为39.8%。测得的社会经济,家庭和儿童行为因素预示着频繁的伤害。结论:结果几乎没有支持学龄前儿童遗传易伤性状的概念。环境影响是该样本中大多数伤害差异的原因。但是,行为变量,尤其是孩子的外部问题行为,对于解释意外伤害也很重要。

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