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首页> 外文期刊>Journal of pediatric and adolescent gynecology >Provisional Diagnosis of Early-Onset Beh?et Disease in a 3-Year-Old Girl
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Provisional Diagnosis of Early-Onset Beh?et Disease in a 3-Year-Old Girl

机译:3岁女孩早发行为疾病的临时诊断

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Study Objective: Evaluate for differences in the management of adolescents with polycystic ovarian syndrome (PCOS) across 3 pediatric specialties. Design: Retrospective review of medical records. Setting: Academic children's hospital. Participants: 181 adolescents seen between July 2008 and June 2010 by providers in Pediatric Endocrinology (PEndo), Adolescent Medicine (AMed), or Pediatric and Adolescent Gynecology (PGyn) identified via billing data (ICD-9 code for PCOS, 256.4). Interventions: None. Main Outcome Measures: (1) Percentage of adolescents with a billing diagnosis of PCOS who met diagnostic criteria; (2) Percentage of individuals screened for comorbidities and differences across specialties; (3) Differences in treatment recommendations across specialties; (4) Factors associated with recommendation for metformin and hormonal contraceptives. Results: Thirteen percent of PEndo patients did not meet diagnostic criteria for PCOS; 20% of AMed and PGyn patients did not meet criteria. There were significant differences in rates of screening for obesity, insulin resistance, and Type 2 diabetes. There were significant differences in treatment recommendations for lifestyle changes, metformin, and anti-androgen therapy across specialties. Specialty and obesity were significant predictors of metformin recommendation; specifically PEndo predicted metformin recommendation. PGyn and AMed specialties predicted hormonal contraceptive recommendation. Conclusions: The variability observed among specialties may be due to differences in training, accounting for a range of comfort with aspects of PCOS. Formulation of consensus guidelines for diagnosis and management of PCOS are needed, along with broad educational efforts. By correctly diagnosing, screening for comorbidities, and managing PCOS appropriately during adolescence, providers may reduce the risk for long-term consequences.
机译:研究目的:评估3个儿科专业的多囊卵巢综合征(PCOS)青少年的管理差异。设计:回顾病历。地点:学龄儿童医院。参加者:在2008年7月至2010年6月之间,儿科内分泌(PEndo),青少年医学(AMed)或儿科和青少年妇科(PGyn)的提供者看到了181名青少年,这些数据是通过计费数据(PCOS的ICD-9代码,256.4)确定的。干预措施:无。主要结果指标:(1)符合诊断标准的PCOS计费诊断青少年的百分比; (2)筛查合并症和跨专业差异的个体百分比; (3)不同专业在治疗建议上的差异; (4)与推荐使用二甲双胍和激素避孕药有关的因素。结果:13%的PEndo患者不符合PCOS的诊断标准; AMed和PGyn患者中有20%不符合标准。肥胖,胰岛素抵抗和2型糖尿病的筛查率存在显着差异。不同专业对生活方式改变,二甲双胍和抗雄激素治疗的治疗建议存在显着差异。专业和肥胖是二甲双胍推荐的重要预测指标;特别是PEndo预测的二甲双胍推荐。 PGyn和AMed专业预测荷尔蒙避孕的建议。结论:各专业间观察到的差异可能是由于培训方面的差异,导致对PCOS方面的舒适度有所提高。需要为PCOS的诊断和管理制定共识性指南,并需要进行广泛的教育工作。通过正确地诊断,筛查合并症并在青春期进行适当的PCOS管理,医疗服务提供者可以降低长期后果的风险。

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