A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes.

Bilbao-Ramos P.; Sifontes-Rodriguez S.; Dea-Ayuela M. A.; Bolas-Fernandez F.

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A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes.

机译：一种用于评估细胞内利什曼原虫amastigotes药理活性的荧光方法。

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摘要

In this work a simple and novel method to evaluate the efficacy of compounds on intracellular Leishmania amastigotes by using a fluorometric assay has been developed. The new method is sensitive, easy to perform and scalable for high throughput and therefore it could be validated for screening of new anti-leishmanial agents.

机译：在这项工作中，已开发出一种简单新颖的方法，通过使用荧光测定法评估化合物对细胞内利什曼原虫amastigotes的功效。该新方法灵敏，易于执行且可扩展以实现高通量，因此可以用于筛选新的抗利什曼病制剂。

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来源
《Journal of Microbiological Methods》 |2012年第1期|共4页
作者
Bilbao-Ramos P.; Sifontes-Rodriguez S.; Dea-Ayuela M. A.; Bolas-Fernandez F.;
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原文格式 PDF
正文语种 eng
中图分类微生物研究与微生物实验;
关键词
Leishmania; Drug screening; Intracellular amastigotes; Resazurin;

机译：利什曼原虫;药物筛选;胞内变形虫;刃天青;

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1. A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes. [J] . Bilbao-Ramos P., Sifontes-Rodriguez S., Dea-Ayuela M. A., Journal of Microbiological Methods . 2012,第1期

机译：一种用于评估细胞内利什曼原虫amastigotes药理活性的荧光方法。
2. Evaluation of Boldine Activity against Intracellular Amastigotes of Leishmania amazonensis [J] . Salama Isabel Cristina, Arrais-Lima Cristina, Arrais-Silva Wagner Welber The Korean Journal of Parasitology . 2017,第3期

机译：鲍丝碱对亚马逊利什曼原虫胞内变形虫的活性评价
3. Collaborative evaluation of a fluorometric method for measuring alkaline phosphatase activity in cow's, sheep's, and goat's milk. [J] . Harding F, Garry E Journal of food protection . 2005,第5期

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4. INVESTIGATION OF MONOAMINE OXIDASE INHIBITORY ACTIVITIES OF NEW CHALCONE DERIVATIVES: COMPARISON OF LC-MS/MS AND FLUOROMETRIC METHODS [C] . Umide Demir Ozkay, Nafiz Oncu Can, Serkan Levent, International Mass Spectrometry Conference . 2018

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5. Pharmacological Evaluation of a Synthetic Coumarin Derivative (4-Fluorophenylacetamide-Acetyl Coumarin) for Its Potential Anticancer Activity in Non-Small Cell Lung Cancer Cell Line [D] . Umar, Shweta. 2020

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6. Evaluation of Boldine Activity against Intracellular Amastigotes of Leishmania amazonensis [O] . Isabel Cristina Salama, Cristina Arrais-Lima, Wagner Welber Arrais-Silva 2017

机译：鲍丝碱对亚马逊利什曼原虫胞内变形虫的活性评价
7. Evaluation of Boldine Activity against Intracellular Amastigotes of Leishmania amazonensis [O] . Isabel Cristina Salama, Cristina Arrais-Lima, Wagner Welber Arrais-Silva 2017

机译：对吉尔曼岛亚马逊细胞内癫痫发球菌的评价
8. Macrophage Activation to Kill Leishmania Tropica: Characterization of P/J Mouse Macrophage Defects for Lymphokine-Induced Antimicrobial Activities Against Leishmania Tropica Amastigotes. [R] . Nacy, C. A., Meltzer, M. S., Fortier, A. H. 1984

机译：巨噬细胞激活杀死利什曼原虫Tropica：表征p / J小鼠巨噬细胞缺陷的淋巴因子诱导抗真菌活性对利什曼原虫Tmasica amastigotes。

A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes.

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