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Asymptotic theory of an infectious disease model

机译:传染病模型的渐近理论

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In this paper, we present asymptotic theory as a viable alternative solution method for infectious disease models. We consider a particular model of a pathogen attacking a host whose immune system responds defensively, that has been studied previously [Mohtashemi and Levins in J. Math. Biol. 43: 446-470 (2001)]. On rendering this model dimensionless, we can reduce the number of parameters to two and note that one of them has a large value that suggests an asymptotic analysis. On doing this analysis, we obtain a satisfying qualitative description of the dynamic evolution of each population, together with simple analytic expressions for their main features, from which we can compute accurate quantitative values.
机译:在本文中,我们提出渐近理论作为传染病模型的可行替代解决方法。我们考虑了一种病原体攻击宿主免疫系统作出防御反应的宿主的特定模型,该模型先前已经研究过[Mohtashemi和Levins,J。Math。生物学43:446-470(2001)]。在使该模型成为无量纲模型时,我们可以将参数的数量减少到两个,并注意其中一个参数的值较大,这表明需要进行渐近分析。在进行此分析时,我们获得了每个种群动态演变的令人满意的定性描述,并为其主要特征提供了简单的解析表达式,从而可以计算出准确的定量值。

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