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首页> 外文期刊>Journal of Functional Foods >Oregano essential oil decreased susceptibility to oxidative stress-induced dysfunction of intestinal epithelial barrier in rats
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Oregano essential oil decreased susceptibility to oxidative stress-induced dysfunction of intestinal epithelial barrier in rats

机译:牛至精油降低大鼠对氧化应激诱导的肠上皮屏障功能障碍的敏感性

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The protective effects of oregano essential oils (OEO) against oxidative stress in intestine of rats were investigated. The results showed that rats orally treated with 5 or 20 mg/kg BW with OEO abolished diquat-induced oxidative stress in jejunum, thereby maintaining jejunal architecture. The protective effect of OEO might cause modification of selected intestinal microbiota, inhibition of inflammatory cytokine expression and subsequent increased occludin expression in jejunum by enhancement of antioxidative capacity. These results revealed that OEO exerted a protective effect against diquat-induced oxidative injury in intestine of rats. (C) 2015 Elsevier Ltd. All rights reserved.
机译:研究了牛至精油(OEO)对大鼠肠道氧化应激的保护作用。结果表明,口服OEO 5或20 mg / kg BW的大鼠消除了敌草快引起的空肠氧化应激,从而维持了空肠结构。 OEO的保护作用可能通过增强抗氧化能力,导致所选肠道菌群的修饰,炎症细胞因子表达的抑制以及空肠中occludin表达的增加。这些结果表明,OEO对敌草快致大鼠肠的氧化损伤具有保护作用。 (C)2015 Elsevier Ltd.保留所有权利。

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