Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection

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Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection

机译：达卡他韦加西美派韦联合利巴韦林或不联合利巴韦林治疗慢性丙型肝炎病毒基因型1感染

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Background & Aims: We evaluated the combination of daclatasvir (pan-genotypic NS5A inhibitor) and simeprevir (NS3/4A protease inhibitor), with or without ribavirin, in hepatitis C virus genotype 1-infected patients.

机译：背景与目的：我们评估了在有或没有利巴韦林的情况下，达卡他韦（泛基因型NS5A抑制剂）和西美普韦（NS3 / 4A蛋白酶抑制剂）的联合治疗对丙型肝炎病毒基因型1感染患者的影响。

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《Journal of Hepatology: The Journal of the European Association for the Study of the Liver》 |2016年第2期|共9页
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Hepatitis C virus; Genotype 1; Direct-acting antiviral; All-oral therapy; Daclatasvir; NS5A inhibitor; Simeprevir; NS3 protease inhibitor;

机译：丙型肝炎病毒;基因型1;直接作用抗病毒药;全口服治疗;达卡他韦;NS5A抑制剂;西美普韦;NS3蛋白酶抑制剂;

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专利

1. Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection [J] . Journal of Hepatology: The Journal of the European Association for the Study of the Liver . 2016,第2期

机译：达卡他韦加西美派韦联合利巴韦林或不联合利巴韦林治疗慢性丙型肝炎病毒基因型1感染
2. A phase 3, open-label study of daclatasvir plus asunaprevir in Asian patients with chronic hepatitis C virus genotype 1b infection who are ineligible for or intolerant to interferon alfa therapies with or without ribavirin (vol 31, pg 1860, 2016) [J] . Wei Lai, Zhang Mingxiang, Xu Min, Journal of gastroenterology and hepatology . 2017,第3期

机译：在亚洲慢性丙型肝炎病毒基因型1B感染中的亚洲患者Daclatasvir Plus Asunaprevir的开放标签研究，患有有或没有利韦利林（Vol 31，PG 1860,2016）的干扰素Alfa疗法
3. A phase 3, open-label study of daclatasvir plus asunaprevir in Asian patients with chronic hepatitis C virus genotype 1b infection who are ineligible for or intolerant to interferon alfa therapies with or without ribavirin [J] . Wei Lai, Zhang Mingxiang, Xu Min, Journal of gastroenterology and hepatology . 2016,第11期

机译：达卡他韦加阿舒那普韦在亚洲慢性丙型肝炎病毒基因型1b感染患者中进行或不接受或不接受利巴韦林干扰素阿尔法治疗的3期开放标签研究
4. DIFFERENTIAL HUMORAL RESPONSE OF GENOTYPE IB HEPATITIS C VIRUS F PROTEIN BETWEEN CHRONIC AND RECOVERED INFECTIONS [C] . Deng Xiaozhao, Kong Jing, Chu Chunli, Progress on post-genome technologies and modern natural products . 2011

机译：慢性感染和康复感染之间基因型IB型肝炎C病毒F蛋白的差异性尿液反应
5. Ribavirin systemic and intracellular exposure and its role on viral response and anemia in chronic hepatitis c genotype 1 infection [D] . Wu, Liviawati Sutjandra. 2015

机译：利巴韦林全身和细胞内暴露及其在慢性丙型肝炎基因型1感染中对病毒反应和贫血的作用
6. Outcomes and predictors of treatment response with sofosbuvir plus daclatasvir with or without ribavirin in Egyptian patients with genotype 4 hepatitis C virus infection [O] . Ossama A Ahmed, Mohamed A Elsebaey, Mohamed Hassan A Fouad, 2018

机译：埃及索非布韦联合达卡他韦联合利巴韦林或不联合利巴韦林治疗的结果和预测因素患者均感染基因型4型丙型肝炎病毒
7. Outcomes and predictors of treatment response with sofosbuvir plus daclatasvir with or without ribavirin in Egyptian patients with genotype 4 hepatitis C virus infection [O] . Ossama A. Ahmed, Mohamed A Elsebaey, Mohamed Hassan Ahmed Fouad, 2018

机译：与埃及患者基因型4丙型肝炎病毒感染的埃及患者有或没有利巴韦林治疗反应的结果和预测因子。

Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection

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