Pattern recognition of HER-1 in biological fluids using stochastic sensing

摘要

Stochastic sensing was employed for pattern recognition of HER-1 in biological fluids. Nanostructured materials such as 5,10,15,20-tetraphenyl-21H, 23H-porphyrin, maltodextrin and a-cyclodextrin were used to modify diamond paste for stochastic sensing of HER-1. Pattern recognition of HER-1 in biological fluids was performed in a linear concentration range between 5.60 x 10(-11) and 9.72 x 10(-7) mg ml(-1). The lower limits of determination (10(-12) mg ml(-1) magnitude order) were recorded when maltodextrin and a-cyclodextrin were used for stochastic sensing. The pattern recognition test of HER-1 in biological fluids samples shows high reliability for both qualitative and quantitative assay.