首页> 外文期刊>Journal of enzyme inhibition and medicinal chemistry. >Adenosine deaminase in ischemia reperfusion injury in patients with myocardial infarction.
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Adenosine deaminase in ischemia reperfusion injury in patients with myocardial infarction.

机译:腺苷脱氨酶在心肌梗死患者缺血再灌注中的作用。

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摘要

A comparative study on the levels of erythrocyte adenosine deaminase and lipid peroxidation has been undertaken in patients with myocardial infarction before and after thrombolysis along with matched healthy individuals. Our findings show that adenosine deaminase activity is highly elevated in post-reperfused patients when compared to pre- thrombolysed and healthy persons. Malondialdehyde(MDA) levels are also significantly increased in post-thrombolysed patients. The study reveals an important role of adenosine deaminase in reperfusion injury in patients with myocardial infarction.
机译:在溶栓前后,与匹配的健康个体进行了心肌梗死患者红细胞腺苷脱氨酶和脂质过氧化水平的比较研究。我们的研究结果表明,与血栓溶解前和健康人相比,再灌注后患者的腺苷脱氨酶活性大大提高。血栓溶解后患者的丙二醛(MDA)水平也显着增加。该研究揭示了腺苷脱氨酶在心肌梗死患者再灌注损伤中的重要作用。

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