Determination of carbamazepine in aquatic organisms by liquid-liquid extraction and liquid chromatography-tandem mass spectrometry

摘要

A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for the determination of carbamazepine in microgram quantities of crustacean Thamnocephalus platyurus and the algae Pseudokirchneriella subcapitata at the ng L~(-1) level. This fully validated method applied to a bioaccumulation study was found suitable for the detection of carbamazepine in small aquatic tissues.