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Computing the dynamics of biomembranes by combining conservative level set and adaptive finite element methods

机译:结合保守水平集和自适应有限元方法计算生物膜的动力学

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The numerical simulation of the deformation of vesicle membranes under simple shear external fluid flow is considered in this paper. A saddle-point approach is proposed for the imposition of the fluid incompressibility and the membrane inextensibility constraints, through Lagrange multipliers defined in the fluid and on the membrane respectively. Using a level set formulation, the problem is approximated by mixed finite elements combined with an automatic adaptive mesh procedure at the vicinity of the membrane boundary. Numerical experiments show that this combination of the saddle-point and adaptive mesh method enhances the robustness of the method. The effect of inertia on the stability of the vesicle in a shear flow is also investigated.
机译:本文考虑了简单剪切外力作用下囊泡膜变形的数值模拟。提出了一种鞍点方法,通过分别在流体和膜上定义的拉格朗日乘数来施加流体不可压缩性和膜不可拉伸性约束。使用水平集公式,可以通过在膜边界附近结合混合有限元和自动自适应网格程序来近似解决问题。数值实验表明,鞍点和自适应网格方法的结合增强了该方法的鲁棒性。还研究了惯性对剪切流中囊泡稳定性的影响。

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