Synthesis of dialkyl 9-chloro-3H-pyrrolo[1,2-a]indole-2,3-dicarboxylates mediated by vinylphosphonium salts

摘要

The addition of a dialkyl acetylenedicarboxylate to 3-chloroindole-2-carboxaldehyde in the presence of triphenylphosphine leads initially to a vinyl phosphonium salt, which undergoes an intramolecular Wittig reaction to produce the title compounds in fairly good yields. [References: 8]