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A new phenylethanoid glycoside from Incarvillea compacta

机译:紧凑型Incarvillea compacta的一种新的苯乙醇类苷

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摘要

A new phenylethanoid glycoside, 3 '''-O-methylcampneoside I (1), was isolated from the 90% ethanolic extract of the roots of Incarvillea compacta, together with three known compounds, campneoside I (2), ilicifolioside A (3), and campneoside II (4). Their structures were determined spectroscopically and compared with previously reported spectral data. Compound 1 existed as epimers and displayed better 1,1-diphenyl-2-picrylhydrazyl (DPPH)-free radical scavenging activity using di-tert-butyl-4-methylphenol (BHT) as the positive control. In addition, pretreatment of human HepG2 cells with compound 1 significantly increased the viability on CCl4-induced cell death.
机译:从90%紧凑型Incarvillea compacta根的乙醇提取物中分离出一种新的苯乙酮类糖苷3'''-O-甲基樟脑苷I(1),以及三种已知化合物樟脑苷I(2)和ilicifolioside A(3) ,和樟脑苷II(4)。通过光谱确定其结构,并与先前报道的光谱数据进行比较。化合物1以差向异构体的形式存在,并使用-4-叔丁基-4-甲基苯酚(BHT)作为阳性对照,表现出更好的1,1-二苯基-2-吡啶基肼基(DPPH)自由基清除活性。此外,用化合物1预处理人HepG2细胞可显着提高CCl4诱导的细胞死亡的生存能力。

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