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Psychiatric disorders among survivors of the Oklahoma City bombing.

机译:俄克拉荷马城爆炸案幸存者中的精神疾病。

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CONTEXT: Disasters expose unselected populations to traumatic events and can be used to study the mental health effects. The Oklahoma City, Okla, bombing is particularly significant for the study of mental health sequelae of trauma because its extreme magnitude and scope have been predicted to render profound psychiatric effects on survivors. OBJECTIVE: To measure the psychiatric impact of the bombing of the Alfred P. Murrah Federal Building in Oklahoma City on survivors of the direct blast, specifically examining rates of posttraumatic stress disorder (PTSD), diagnostic comorbidity, functional impairment, and predictors of postdisaster psychopathology. DESIGN, SETTING, AND PARTICIPANTS: Of 255 eligible adult survivors selected from a confidential registry, 182 (71%) were assessed systematically by interviews approximately 6 months after the disaster, between August and December 1995. MAIN OUTCOME MEASURES: Diagnosis of 8 psychiatric disorders, demographic data, level of functioning, treatment, exposure to the event, involvement of family and friends, and physical injuries, as ascertained by the Diagnostic Interview Schedule/Disaster Supplement. RESULTS: Forty-five percent of the subjects had a postdisaster psychiatric disorder and 34.3% had PTSD. Predictors included disaster exposure, female sex (for any postdisaster diagnosis, 55% vs 34% for men; chi2 = 8.27; P=.004), and predisaster psychiatric disorder (for PTSD, 45% vs 26% for those without predisaster disorder; chi2 = 6.86; P=.009). Onset of PTSD was swift, with 76% reporting same-day onset. The relatively uncommon avoidance and numbing symptoms virtually dictated the diagnosis of PTSD (94% meeting avoidance and numbing criteria had full PTSD diagnosis) and were further associated with psychiatric comorbidity, functional impairment, and treatment received. Intrusive reexperience and hyperarousal symptoms were nearly universal, but by themselves were generally unassociated with other psychopathology or impairment in functioning. CONCLUSIONS: Our data suggest that a focus on avoidance and numbing symptoms could have provided an effective screening procedure for PTSD and could have identified most psychiatric cases early in the acute postdisaster period. Psychiatric comorbidity further identified those with functional disability and treatment need. The nearly universal yet distressing intrusive reexperience and hyperarousal symptoms in the majority of nonpsychiatrically ill persons may be addressed by nonmedical interventions of reassurance and support.
机译:背景:灾难使未选中的人群遭受创伤事件的折磨,可用于研究心理健康影响。俄克拉荷马州俄克拉荷马城爆炸案对研究创伤的心理健康后遗症特别重要,因为据预测,爆炸的极端程度和范围将对幸存者产生深远的精神影响。目的:测量在俄克拉荷马市的Alfred P. Murrah联邦大楼遭到炸弹袭击对直接爆炸幸存者的精神影​​响,特别是检查创伤后应激障碍(PTSD)的发生率,诊断合并症,功能障碍以及灾后心理病理学的预测指标。设计,地点和参与者:在从机密注册表中选择的255位合格的成年幸存者中,在灾难发生大约6个月后(1995年8月至12月),通过访谈系统地评估了182名(71%)。主要观察指标:诊断8例精神疾病。 ,人口统计学数据,功能水平,治疗,事件发生的风险,家人和朋友的参与以及人身伤害,具体取决于诊断性访谈时间表/灾难补遗。结果:45%的受试者患有灾后精神病,而34.3%的受试者患有PTSD。预测因素包括灾难暴露,女性(对于任何灾后诊断,男性分别为55%和34%; chi2 = 8.27; P = .004)和灾难前精神疾病(对于PTSD,对于没有灾难前疾病的人而言为45%vs 26%); chi2 = 6.86; P = .009)。 PTSD的发病迅速,有76%的患者报告当天发病。相对少见的回避和麻木症状实际上决定了PTSD的诊断(94%符合回避和麻木标准的患者对PTSD进行了全面诊断),并且进一步与精神病合并症,功能障碍和接受的治疗有关。侵入性体验和过度兴奋的症状几乎普遍存在,但其自身通常与其他精神病理学或功能障碍无关。结论:我们的数据表明,对避免和麻木症状的关注本来可以为PTSD提供有效的筛查程序,并且可以在灾难后的早期识别出大多数精神病病例。精神病合并症进一步确定了那些有功能障碍和治疗需要的人。在大多数非精神病患者中,几乎普遍但令人不安的侵入性体验和过度兴奋的症状可以通过保证和支持的非医学干预来解决。

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