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Davies and Welch draw unfounded conclusions about thyroid cancer from epidemiological data: Reply

机译:戴维斯和韦尔奇从流行病学数据得出关于甲状腺癌的毫无根据的结论:回复

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Ms Banach suggests that improvements in diagnosis and treatment over the past 30 years might explain a stable thyroid cancer mortality rate in the face of skyrocketing incidence. We agree that this is "possible," but it is not plausible. To produce stable mortality, these improvements would have had to exactly match the change in incidence rate. If the improvements occurred too fast, mortality would fall; if the improvements, occurred too slowly, mortality would rise. The most parsimonious explanation is that the vast reservoir of sub-clinical cancer is increasingly being detected, and this newly diagnosed disease is not destined to cause death.
机译:Banach女士建议,在过去30年中,诊断和治疗的改善可能解释了面对暴涨的发病率,甲状腺癌死亡率稳定的原因。我们同意这是“可能的”,但不是合理的。为了产生稳定的死亡率,这些改善必须与发病率的变化完全匹配。如果改善得太快,死亡率将下降;如果改善太慢,死亡率将会上升。最简约的解释是,越来越多的亚临床癌症库被发现,这种新诊断出的疾病注定不会导致死亡。

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