CHIRALITY CONTROL OF TROPOS DIPHENYLMETHANE-DERIVED PHOSPHORAMIDITES BY CHIRAL DIENES: ITS APPLICATION TO ASYMMETRIC MICHAEL ADDITION

摘要

The Rh complex of tropos diphenylmethane-derived phosphoramidite could be chirally controlled to adopt single chiral conformation upon addition of a chiral diene. In the asymmetric Michael addition of α-cyanocarboxylates catalyzed by the Rh complexes, the chiral diene and bisphenylmethane-derived phosphoramidite functioned to attain higher enantioselectivity and catalytic activity via asymmetric activation.