A PRACTICAL SYNTHETIC METHOD FOR #alpha#-AND #beta#-GLYCOSYLOXYACETIC ACIDS

摘要

Dihydroxylation of allyl 2,3,4-tri-O-benzyl-6-O-tritylglycosides provides diols,the anomers of which can easily be separated by column chrmatography in a practical scale.These anomers can be cleanly transformed into #alpha#-and #beta#-glycosyloxyacetic acdis,respectively,via oxidative cleavage of the diol followed by oxidation.