Practical synthetic methods for three unstable, unsaturated bromomethyl ketones, and on the use of near-orthogonal experiments for synthetic exploration.

摘要

Paper I, II, III, IV and V are not available in Munin: I: Alemayehu Mekonnen, Andreas Westerlund, Martina Havelkova, AlexandreDescomps & Rolf Carlson: 'Synthesis of 1-Bromo-3- butyn-2-one and 1,3- Dibromo-3-buten-2-one', available in II: Rolf Carlson, Alexandre Descomps, Alemayehu Mekonnen, Andreas Westerlund,& Martina Havelkova: 'Improved synthesis of 1-Bromo-3-buten-2-one', available in III: Descomps, A.; Carlson, R.: 'Deprotection of Acetals from Unsaturated, Unstable Bromoketones', available in IV: Carlson, R.; Simonsen, G.; Descomps, A.; Carlson, J. E.: 'Orthogonal Experiments in the Development of Organic Synthetic Processes', available in V: Carlson, R.; Simonsen, G.; Descomps, A.; Carlson, J. E.: 'Identification of Important Experimental Variables in Organic Synthetic Procedures by Near-Orthogonal Experiments', available in