Statin therapy works for patients who have type 2 diabetes.

摘要

Coronary heart disease (CHD) remains the leading cause of death in the United States, resulting in more deaths per year than the next five leading causes of death combined. Although prevention and intervention efforts have been lowering the CHD mortality rate, clinical progress is being undercut by rising rates of obesity and type 2 diabetes mellitus .(DM), as well as by reduced adherence to evidence-based prevention efforts by caregivers. Statin therapy-coupled with lifestyle changes such as a heart-healthy diet, weight loss, and exercise-has been shown to be effective at reducing cholesterol levels in patients with established cardiovascular disease. Statins have helped to reduce morbidity and mortality in this patient group, but one question has remained: Can statins achieve an equivalent effect in persons with type 2 DM?