Immunology and the evaluation of risk factors for development of spontaneous bacterial peritonitis.

摘要

I would like to congratulate .Dr. Campbell for his work that found the lack of an effect of the use of proton pump inhibiters on the incidence of spontaneous bacterial peritonitis (SBP) . Their work certainly increases our understanding of this phenomenon and eases some concerns; however, it is not clear that there may be some underlying differences in their study from the previous work of Dr. Bauer that had found a slightly increased incidence . Nearly 30 years ago my group had an interest in the immunologic mechanisms of infection responsible for spontaneous bacterial peritonitis and, several years later, also in the mechanisms of peritonitis associated with peritoneal dialysis (CAPD) [4, 5].