Prospective and retrospective recording of severe hypoglycaemia, and assessment of hypoglycaemia awareness in insulin-treated Type 2 diabetes.

摘要

Reported rates of severe hypoglycaemia (SH) in insulin-treated Type 2 diabetes vary widely [1,2]. In contrast to Type 1 diabetes [3], methods for assessment of hypoglycaemia awareness have not been prospectively tested in Type 2 diabetes. We addressed these issues in a 1-year prospective study of 121 outpatients with insulin-treated Type 2 diabetes (Table 1). Events of SH, defined as need for assistance from others to treat the condition, were reported by telephone within 24 h after the incident and recorded in bimonthly questionnaires. These rates were compared with reports of SH during the preceding year obtained at baseline and at the end of study [4]. We also assessed the feasibility and reproducibility of a classification of hypoglycaemia awareness previously validated in Type 1 diabetes [4]. This method classifies patients with normal, impaired or severely impaired awareness of hypoglycaemia according to the answers to a screening question.