Surgical therapy of lung metastases from head and neck cancer [Chirurgische Therapie pulmonaler Metastasen von Kopf-Hals-Tumoren]

摘要

Pulmonary metastasectomy is an established procedure in oncological therapeutic concepts. A systematic literature search and an analysis of all studies published since 01.01.2000 should evaluate the advantage of pulmonary metastasectomy for patients with primary head and neck cancer. Lung metastases develop in 1.9–13 % of head and neck cancer patients. Following metastasectomy, patients reach a median survival of 9.5–78 months and 5-year survival rates of up to 58 % are achieved. Intrathoracic recurrence occurs in 18.4–81.8 % of patients, selected instances of which can be successfully treated by remetastasectomy. Patients with squamous cell carcinoma have the worst prognosis, but could also become long-term survivors (≥ 60 months). Pulmonary metastasectomy is frequently the only potentially curative therapeutic approach and offers a better long-term survival than nonsurgical therapies. Lung metastasectomy is thus the treatment of choice in selected patients with pulmonary metastases from primary head and neck cancer.