Efficacy and Tolerability of Ginkgo Extract in Treatment of Alzheimer's Disease and Vascular Dementia

摘要

Many studies have demonstrated the safety and efficacy of 240 mg (120 mg 2x/day) of ginkgo {Ginkgo biloba, Ginkgoaceae) special extract EGb 761°° (Dr. Willmar Schwabe GmbH and Co. KG Pharmaceuticals; Karlsruhe, Germany). Patient compliance is betterwhen patients are required to take fewer daily doses. Therefore, the manufacturer developed a once-daily 240 mg dose of EGb 761. The once-daily dose was tested and found to be safe and efficacious in a previous trial.1 The goal of the present study wasto learn more about efficacy in different types of dementia. This was accomplished by conducting a subgroup analysis of the total population of a randomized, controlled, double-blind, multicenter study.