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Esophageal perforation--associated risk with balloon tamponade after endoscopic therapy. Myth or reality?

机译:食管穿孔-内镜治疗后与球囊填塞相关的风险。神话还是现实?

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BACKGROUND/AIMS: Variceal bleeding is still associated with high mortality and balloon tamponade may be a lifesaving measure when endoscopic therapy is not available or feasible. The risk of esophageal perforation with balloon tamponade after endoscopic therapy is still uncertain. The aims of the study were to investigate balloon tamponade effectiveness and safety after endoscopic therapy. METHODOLOGY: Retrospective analysis of 100 consecutive episodes of acute variceal bleeding treated with the Sengstaken-Blakemore tube. RESULTS: Balloon tamponade had an overall effectiveness of 61%. The Child-Pugh score was significantly higher in patients who failed balloon tamponade. In 48 cases balloon tamponade was preceded by failure of endoscopic therapy. Balloon tamponade was more effective if a previous attempt to perform endoscopic therapy happened (75% vs. 48%; p = 0.006). Aspiration was the most frequent complication. No cases of esophageal perforation were registered. CONCLUSIONS: Currently balloon tamponade is only used as a temporary bridge to other strategies, when other forms of hemostatic therapies do not succeed. Balloon tamponade was more effective in patients with less severe hepatic dysfunction. Previous attempts to perform endoscopic therapy may augment tamponade effectiveness without increasing the risk of esophageal perforation.
机译:背景/目的:静脉曲张破裂出血仍与高死亡率相关,当内窥镜治疗不可行或不可行时,球囊填塞可能是一种挽救生命的措施。内镜治疗后食管穿孔伴球囊填塞的风险仍不确定。该研究的目的是研究内镜治疗后球囊填塞的有效性和安全性。方法:回顾性分析Sengstaken-Blakemore管治疗的100例急性静脉曲张破裂出血。结果:球囊填塞总体有效率为61%。在球囊压塞失败的患者中,Child-Pugh评分明显更高。在48例球囊填塞术之前,内镜治疗失败。如果先前尝试进行内镜治疗,则球囊填塞更为有效(75%比48%; p = 0.006)。抽吸是最常见的并发症。没有记录到食管穿孔的病例。结论:目前,当其他形式的止血疗法未能成功时,球囊填塞仅用作其他策略的临时桥梁。球囊填塞对轻度肝功能不全的患者更有效。之前进行内窥镜治疗的尝试可能会增加填塞效果,而不会增加食管穿孔的风险。

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