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PedMIDAS-based scoring underestimates migraine disability on non-school days

机译:基于PedMIDAS的评分低估了非上学日的偏头痛

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摘要

Objective The aim of this study is to compare daily Pediatric Migraine Disability Assessment (PedMIDAS)-based scores for headaches occurring on school days vs non-school days and during the school year vs the summer holiday. Background The PedMIDAS is the only instrument validated to assess migraine disability among school-aged children. However, the PedMIDAS may underestimate disability during prolonged school holidays. Methods In a prospective cohort study, migraine patients aged 10-18 years completed a 90-day Internet-based headache diary. For each headache day, they answered PedMIDAS-based questions and rated their headache intensity (scale 1-10). PedMIDAS-based scores, headache intensity ratings, and relative headache frequencies were compared for school days vs non-school days and for the school year vs the summer holiday. Results Fifty-two patients completed 4680 diary entries comprising 984 headache days. The headache frequencies and intensity ratings did not differ between time periods. However, the mean headache disability scores (as measured from PedMIDAS-based questions) were significantly different for school days (0.85) compared to non-school days (0.45), P-<-.001, and for the school year (0.73) compared to the summer holiday (0.46), P-<-.016. Conclusion Given similar headache intensities and frequencies, daily PedMIDAS-based scores significantly underestimate headache disability on non-school days. Accordingly, PedMIDAS scoring during the school year may not be comparable to assessments done during the summer holiday. These potential differences must be considered when using the instrument as an outcome measure for clinical trials.
机译:目的这项研究的目的是比较每日基于小儿偏头痛评估(PedMIDAS)的分数,以评估在上学日与非上学日以及学年与暑假期间发生的头痛。背景技术PedMIDAS是唯一经验证可评估学龄儿童偏头痛残疾的仪器。但是,PedMIDAS可能会低估长时间学校假期期间的残疾。方法在一项前瞻性队列研究中,年龄在10-18岁的偏头痛患者完成了90天的基于互联网的头痛日记。对于每天头痛的每一天,他们都会回答基于PedMIDAS的问题,并对头痛的强度进行评分(等级1-10)。比较了基于PedMIDAS的得分,头痛强度等级和相对头痛发生频率,比较了上学日和非上学日,以及学年和暑假。结果52例患者完成了4680次日记输入,包括984天头痛。头痛频率和强度等级在不同时间段之间没有差异。但是,与非上课日(0.45),非上课日(0.45),P-<-。001和上学年(0.73)相比,上课日(0.85)的平均头痛残疾评分(根据基于PedMIDAS的问题进行衡量)差异显着与暑假(0.46)相比,P-<-。016。结论在头痛强度和频率相似的情况下,基于PedMIDAS的每日评分显着低估了非上学日的头痛残疾。因此,在学年期间的PedMIDAS评分可能无法与暑假期间进行的评估相提并论。当使用该仪器作为临床试验的结果指标时,必须考虑这些潜在的差异。

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