Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma

Choi Kyu Young; Choi Hyung-Joon; Chung Eun-Jae; Lee Dong Jin; Kim Jin Hwan; Rho Young-Soo

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Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma

机译：口腔鳞状细胞癌中乳腺丝氨酸蛋白酶抑制剂（maspin）和p53在染色体17和18的杂合性丧失

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BackgroundThe purpose of this study was to evaluate the loss of heterozygosity (LOH) in chromosomes 17p13 (p53 gene) and in 18q21 (mammary serine protease inhibitor [maspin] gene), and the expression of both genes in tissues, in patients with oral cavity squamous cell carcinoma (SCC).

机译：背景本研究的目的是评估口腔患者17p13染色体（p53基因）和18q21（乳腺丝氨酸蛋白酶抑制剂[maspin]基因）中杂合性（LOH）的丧失，以及这两种基因在组织中的表达鳞状细胞癌（SCC）。

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《Head and neck: Journal for the sciences and specialities of the head and neck》 |2015年第9期|共7页
作者
Choi Kyu Young; Choi Hyung-Joon; Chung Eun-Jae; Lee Dong Jin; Kim Jin Hwan; Rho Young-Soo;
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正文语种 eng
中图分类颈部外科学;
关键词
p53; mammary serine protease inhibitor (maspin); loss of heterozygosity; oral cavity; squamous cell carcinoma;

机译：p53;乳腺丝氨酸蛋白酶抑制剂（maspin）;杂合性缺失;口腔;鳞状细胞癌;

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1. Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma [J] . Choi Kyu Young, Choi Hyung-Joon, Chung Eun-Jae, Head and neck: Journal for the sciences and specialities of the head and neck . 2015,第9期

机译：口腔鳞状细胞癌中乳腺丝氨酸蛋白酶抑制剂（maspin）和p53在染色体17和18的杂合性丧失
2. Subcellular Expression of Mammary Serine Proteinase Inhibitor (MASPIN) in Locally Advance Oral Squamous Cell Carcinoma [J] . Samina Zaheer, Abdul Hannan Nagi Journal of Interdisciplinary Histopathology . 2014,第4期

机译：乳腺丝氨酸蛋白酶抑制剂（MASPIN）在局部晚期口腔鳞状细胞癌中的亚细胞表达
3. Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness [J] . BabaT., KawaguchiM., FukushimaT., Journal of Pathology: Journal of the Pathological Society of Great Britain and Ireland . 2012,第2期

机译：膜结合丝氨酸蛋白酶抑制剂HAI-1的丢失诱导口腔鳞状细胞癌细胞的侵袭性
4. The Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 (Iressa) Suppresses Proliferation and Invasion of Human Oral Squamous Carcinoma Cells via p53 Independent and MMP, uPAR Dependent Mechanism [C] . EUN JU LEE, JIN HA WHANG, NAM KYEONG JEON, Meeting on Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets . 2007

机译：表皮生长因子受体酪氨酸激酶抑制剂ZD1839（Iressa）通过独立于p53和MMP，uPAR依赖性机制抑制人口腔鳞状细胞癌细胞的增殖和侵袭
5. Effects of isoflavones and glycolytic enzyme inhibitors on regulation of proliferation and signaling pathways in oral squamous cell carcinoma cells (SCC15, SCC25): A mechanistic study [D] . Johnson, Tara Bardsley 2007

机译：异黄酮和糖酵解酶抑制剂对口腔鳞状细胞癌细胞（SCC15，SCC25）增殖和信号通路的调节作用的机理研究
6. Loss of Heterozygosity on Chromosomes 3p 8p 9p and 17p in the Progression of Squamous Cell Carcinoma of the Larynx [O] . Woo Jeong Yoo, Seung Ho Cho, Youn Soo Lee, 2004

机译：喉鳞状细胞癌发展过程中3p8p9p和17p染色体杂合性的丧失
7. Subcellular Expression of Mammary Serine Proteinase Inhibitor (MASPIN) in Locally Advance Oral Squamous Cell Carcinoma [O] . Samina Zaheer, Abdul Hannan Nagi 2014

机译：乳腺癌蛋白酶抑制剂（maspIN）在局部晚期口腔鳞状细胞癌中的亚细胞表达
8. Combined Therapy for Non-Resectable Squamous Cell Carcinoma of the Oral Cavity. Local Selective Intra-Arterial Infusion with Adriamycin and Bleomycin Combined Concurrently with Radiotherapy. The Predictive Value of Flow Cytometry in Monitoring Cell Cycle Kinetic Effects of Therapy [R] . Noorman van der Dussen, M. F. 1986

机译：口腔不可切除鳞状细胞癌的联合治疗。局部选择性动脉内注射阿霉素和博来霉素联合放疗。流式细胞术在监测细胞周期动力学疗效中的预测价值

Loss of heterozygosity in mammary serine protease inhibitor (maspin) and p53 at chromosome 17 and 18 in oral cavity squamous cell carcinoma

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