FIELD: biotechnology.;SUBSTANCE: invention refers to biotechnology, medicine and molecular biopharmacology. Disclosed is use of a polypeptide having an amino acid sequence corresponding to SEQ ID NO:1 to suppress viability, migration and invasion of squamous cell carcinoma of the oral cavity, reducing expression of oncogenes ITGAV, BCL2 and MMP7.;EFFECT: use of the invention provides higher anticancer efficacy of endostatin protein with respect to squamous cell carcinoma of the oral cavity.;1 cl, 7 dwg
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机译:技术领域:发明:涉及生物技术,医学和分子生物药理学。公开了具有对应于SEQ ID NO:1的氨基酸序列的多肽在抑制口腔鳞状细胞癌的生存力,迁移和侵袭,减少癌基因ITGAV,BCL2和MMP7的表达中的用途;效果:使用本发明提供了内皮抑素蛋白相对于口腔鳞状细胞癌的更高的抗癌功效。; 1 cl,7 dwg
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