The necessity and reliability of intraoperative parathyroid hormone (PTH) Testing in patients with mild hyperparathyroidism and PTH levels in the normal range

摘要

We read with interest the article by Alhefdhi et al. [1] and discussed it in our journal club. We congratulate the authors for raising the issue of using intraoperative parathyroid hormone (PTH) monitoring in mild primary hyperparathyroidism (PHPT). Because of the mild biochemical and clinical indicators and the indolent natural course of the disease, surgical intervention and its benefits remain controversial [2]. It is particularly difficult to apply intraoperative adjuncts to decide the surgical cure of the patient when the serum PTH level is within the normal range. Very few studies have focused on this issue [3], and we believe the utility of intraoperative PTH (IOPTH) monitoring in mild PHPT needs to be studied, as the incidence of mild PHPT, common in Western countries, is also becoming prevalent in developing countries.