The 'timing hypothesis' for estrogen therapy in menopausal symptom management

摘要

JoAnn E Manson is Professor of Medicine and the Michael and Lee Bell Professor of Women's Health at Harvard Medical School. She is also Chief of the Division of Preventive Medicine at Brigham and Women's Hospital. She is an endocrinologist, epidemiologist and Principal Investigator of several research studies, including the Women's Health Initiative Clinical Center, Boston site; the VITAL; the cardiovascular disease component of the Nurses' Health Study and the Boston site of the KEEPS trial. Her primary research interests include the role of endogenous and exogenous hormones as determinants of cardiovascular disease, diabetes and other chronic diseases, lifestyle and nutritional factors in prevention of these diseases, and biochemical and genetic factors in risk prediction. She has received numerous honors, including the Woman in Science Award from the American Medical Women's Association, the American Heart Association's Population Research Prize, the American Heart Association's Distinguished Scientist Award, election to the Institute of Medicine of the National Academies and the Bernadine Healy Award for Visionary Leadership in Women's Health. She is a past President of the North American Menopause Society. She has published more than 800 articles and is the author or editor of several books.