Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants.

Foradori A; Mezzano S; Videla C; Pefaur J; Elberg A

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Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants.

机译：通过在稳定的成人肾脏移植中同时使用神经和地尔硫卓或酮康唑来修饰环孢霉素A和代谢物的药代动力学。

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来源
《Transplantation Proceedings》 |1998年第5期|共3页
作者
Foradori A; Mezzano S; Videla C; Pefaur J; Elberg A;
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正文语种 eng
中图分类外科手术学;
关键词
Cyclosporine; Diltiazem; Immunosuppressive Agents; Ketoconazole; Kidney Transplantation; 环孢菌素; 地尔硫ZHUO; 免疫抑制剂; 酮康唑; 肾移植;

机译：Cyclosporine;Diltiazem;Immunosuppressive Agents;Ketoconazole;Kidney Transplantation;环孢菌素;地尔硫|ZHUO;|免疫抑制剂;酮康唑;肾移植;

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专利

1. Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants. [J] . Foradori A, Mezzano S, Videla C, Transplantation Proceedings . 1998,第5期

机译：通过在稳定的成人肾脏移植中同时使用神经和地尔硫卓或酮康唑来修饰环孢霉素A和代谢物的药代动力学。
2. Use of cyclosporine microemulsion (Neoral) in de novo and stable renal transplantation: clinical impact, pharmacokinetic consequences and economic benefits. Canadian and International Neoral Study Groups. [J] . Keown PA Transplantation Proceedings . 1996,第4期

机译：从头使用环孢素微乳剂（Neoral）和稳定的肾移植：临床影响，药代动力学后果和经济效益。加拿大和国际神经研究小组。
3. Significant impacts of CYP3A4*1G and CYP3A5*3 genetic polymorphisms on the pharmacokinetics of diltiazem and its main metabolites in Chinese adult kidney transplant patients [J] . Zhou L. -Y., Zuo X. -C., Chen K., Journal of Clinical Pharmacy and Therapeutics . 2016,第3期

机译：CYP3A4 * 1G和CYP3A5 * 3基因多态性对中国成年肾移植患者地尔硫卓及其主要代谢产物药代动力学的影响
4. Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients [O] . J. S. BLECK, C. THIESEMANN, V. KLIEM, 1996

机译：地尔硫卓增加了稳定的雄性和雌性同种异体肾移植受者中环化环孢菌素代谢物的血药浓度导致不同的环孢菌素代谢物模式
5. Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients [O] . BLECK, J. S., THIESEMANN, C., KLIEM, V., 2003

机译：地尔硫卓增加了稳定的雄性和雌性同种异体肾移植受者中环化环孢菌素代谢物的血药浓度，导致不同的环孢菌素代谢物模式

Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants.

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