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首页> 外文期刊>Trends in Cardiovascular Medicine >Endothelial progenitor cells for cardiovascular regeneration.
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Endothelial progenitor cells for cardiovascular regeneration.

机译:内皮祖细胞用于心血管再生。

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摘要

Endothelial progenitor cells (EPCs) are peripheral blood mononuclear cells that can differentiate into mature endothelial cells. Adult EPCs were first discovered in human peripheral blood in 1997. Since then, the potency of EPCs for cardiovascular regeneration has been demonstrated in several preclinical studies; and investigators are beginning to evaluate the therapeutic utility of EPCs in early-phase clinical trials. This review summarizes the progression of basic, preclinical, and clinical research into the potential use of EPC therapy for cardiovascular regeneration.
机译:内皮祖细胞(EPC)是可以分化为成熟内皮细胞的外周血单核细胞。成人EPCs最早是在1997年从人类外周血中发现的。此后,在一些临床前研究中已经证明了EPCs对心血管再生的作用。研究人员开始在早期临床试验中评估EPC的治疗效用。这篇综述总结了基础,临床前和临床研究在EPC治疗心血管再生中的潜在应用的进展。

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